Naturopathic Medical Research Dragon's Medical Bulletin July Aug 2010

September 2010 Newsletter

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MEDICAL ORIENT EXPRESS

1.Vitamin B2 + Herbal Formula Effective for Recurrent Aphthous Ulcers

Summary: One hundred and seventy-eight patients with recurrent aphthous ulcers were randomized into treatment (n=90) and control groups (n=88). The age, sex, and duration of illness were statistically comparable between both groups. The control group received 0.2g of vitamin B2 three times daily. In addition to vitamin B2, the treatment group received 9g twice daily of ZhiBaiDiHuangWang (知柏地黃丸) manufactured by Tong Ren Tang Technologies Co., Ltd (北京同仁堂科技發展股份有限公司).

All patients were re-assessed after two weeks of treatment. A patient was considered

1) cured, if the ulcer was healed and there was no more pain or discomfort;

2) significantly improved, if erythema was less and the ulcer size reduced;

3) improved, if erythema and pain was reduced, yet the ulcer size was about the same;

4) to show no change, if there was no improvement in signs and symptoms.

Results Comparison after Two Weeks of Treatment

Group	n=	Sig. Improved	Improved	No Change	Recurr. in 3 months
Treatment	90	67 (74.4%)	14 (15.6%)	9 (10%)	8 (8.89%)
Control	88	43 (48.9%)	31 (35.2%)	14 (15.9%)	27 (30.7%)

Results showed that the significant improvement rate in the treatment group was statistically better than that of the control group (P=0.0083), and the overall effectiveness rates were statistically insignificant between both groups (P=0.0712). However, the 3-month recurrence rate was significantly less in the treatment group (P=0.0713).

Meng LQ, et al. Observation on the treatment of recurrent oral ulcer with the eombination of vitamin B2, and Zhibaidihuangwan. Int J Trad Chin Med (Guo Ji Zhong Yi Zhong Yao Za Zhi). 2010 May; 32(3): 239-240.

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2. Moxa on CV-8 through a Ginger Slice Helps Deficient-Cold Type Ulcerative Colitis

Summary: The author assigned 87 patients with colonoscopy-confirmed ulcerative colitis into the treatment (n=57) or control (n=30) groups. The treatment group consisted of 26 males and 31 females, between 20 to 76 years of age, with duration of illness between four months and 12 years. The control group consisted of 18 males and 12 females, between 21 to 65 years of age, with duration of illness between three months and seven years. All patients were diagnosed as “Deficient-Cold” type colitis according to the criteria of Traditional Chinese Medicine. The control group received ShenLingBaiZhuSan (參苓白朮散) based decoction twice daily.

The treatment group received moxibustion (three moxa cones weighing about 3g each) on CV-8 (Shen Que, 神闕) through a slice of fresh ginger (4cm x 4cm, about 1cm thick) once daily. The treatment group received two courses of treatment with one course consisting of twelve treatments. Patients were given three to five days break between courses.

A patient was considered:

1) cured, if diarrhea was resolved and patient resumed normal diet and returned to work;

2) improved, if diarrhea was resolved but may recur occasionally to a lesser extent with eating “cold-natured” foods or emotional upsets;

3) to show no change, if there was no obvious change in signs or symptoms.

Treatment Effectiveness Comparison

Group	n=	Cured	Improved	No Change	Total Effectiveness Rate (%)
Treatment	57	21	30	6	89.47
Control	39	8	13	9	70.00

No Change Total Effectiveness Rate (%) Treatment 57 21 30 6 89.47 Control 30 8 13 9 70.00

Results showed that the differences between the two groups were statistically significant (P<0.05).

Li JX. Inner Mongol Journal of Traditional Chinese Medicine (Nei Meng Gu Zhong Yi Yao). 2010; 29(10): 27-28.

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3.Warming Needle Acupuncture at UB-62 Works for Acute Diarrhea

The authors treated 90 acute diarrhea patients with warming needle acupuncture between 2001 and 2006, and reported satisfactory results. There were 49 males and 41 females between 6 and 67 years old. All patients were either exposed to unsanitary foods or had upper respiratory symptoms immediately prior to the onset of diarrhea. The duration of illness ranged from three hours up to five days: 34 had diarrhea less than 12 hours, 42 had it less than one day, and 14 had it for more than two days.

None had dehydration, electrolyte imbalance or chronic gastrointestinal illness history. All patients received warming needle acupuncture at UB-62 (Shen Mai, 申脈) once daily by burning three 1.5 cm moxa sticks on each needle. Of the 90 patients, 56 were cured after one treatment (62.22%), 23 were cured after two treatments (25.56%), and 11 were cured after three treatments (12.22%); no patient was unaffected by treatment. The authors deemed the treatment to be simple, easy to do, without side-effects, and therefore worthwhile promoting to general practitioners.

Zhe Q, et al. Journa of Sichuan Traditional Chinese Medicine (Si Chuan Zhong Yi). 2008; 26(5): 116.

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